Association of a wide range of chronic diseases and apolipoprotein E4 genotype with subsequent risk of dementia in community-dwelling adults: A retrospective cohort study

Xianwen Shang, Zhuoting Zhu, Xueli Zhang, Yu Huang, Xiayin Zhang, Jiahao Liu, Wei Wang, Shulin Tang, Honghua Yu, Zongyuan Ge, Xiaohong Yang, Mingguang He
March 2022
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Type
Journal article
Publication
eClinicalMedicine
ad aging alzheimer's disease and incidence of dementia apoe4 apolipoprotein e4 area under the curve auc bmi body mass index caide cardiovascular risk factors chronic kidney disease chronic obstructive pulmonary disease ci ckd confidence interval copd dementia framingham heart study frs glycosylated haemoglobin hazard ratio hba1c hdl-c high-density lipoprotein cholesterol hiv hr human immunodeficiency virus icd interaction international classification diseases interquartile range iqr late-onset dementia ldl-c low-density lipoprotein cholesterol major chronic diseases multimorbidity par population attributable risk receiver operating characteristic curve roc sd standard deviation vascular dementia vd young-onset dementia
Xueli Zhang
Xueli Zhang
PhD of Bioinformatics, Assistant Professor

My research interest is to explore the comorbidity relationship of diseases based on complex networks and to find new combination markers, and has constructed multiple biomarker databases and prediction models.